A significant increase in the cholesterol molecules can reduces the diffusion of water across the cell membrane.
How cholesterol molecules affect the diffusion of water across the membrane?
-  cholesterol molecules will block the passage by increasing the packing of phospholipids.
- cholesterol has the ability to fit into the spaces between phospholipids and increase the packing of phospholipids.
- That lead to reduce membrane permeability and hence reduces the diffusion of water and other water-soluble molecules across the membrane. 
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