Which of the following BEST describes catabolite repression of the lac operon? 
O Glucose is the preferred energy source for E. coli. 
O The operon is transcriptionally inactive in the absence of lactose. 
O The operon is transcriptionally active when an activator protein binds to the promoter in the absence of glucose. 
O The operon is transcriptionally inactivated by a repressor protein, which binds to glucose. 
O The operon is repressed by its protein products.